Elysium Health

We’re studying the relationship between NAD+ biology and menopause.

Because menopause deserves a place in the longevity conversation.

Source: Holmes, Holly E., et al. "Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial." Frontiers in Aging 7 (2026).

Menopause is part of the larger story of women’s health and longevity.

A systematic review of 53 studies, representing more than 450,000 women across 28 longitudinal cohorts, found associations between menopausal symptoms and cardiovascular disease, diabetes, psychiatric disorders, and reduced bone mineral density.

The findings don’t establish that menopausal symptoms cause these outcomes, and more research is needed to understand these relationships. The authors conclude that future work, however, should “evaluate whether treating menopausal symptoms could lead to improvements in future health outcomes.”

And they point to an important idea: menopause deserves a place in the longevity conversation.

Source: Andrews, Robin, et al. "The role of menopausal symptoms on future health and longevity: A systematic scoping review of longitudinal evidence." Maturitas 190 (2024).

Congratulations to the 2026 Nobel Prize laureates, whose groundbreaking contributions across science, literature, peace, and economics continue to push the boundaries of human knowledge and progress.

Elysium is proud to be part of a scientific community advancing our understanding of human biology and health, and to support the work of world-class researchers around the globe. That’s why nine Nobel laureates have served on our Scientific Advisory Board.

Explore the groundbreaking discoveries and achievements of the 2026 Nobel Prize laureates:

All Nobel Prizes All Nobel Prizes

What if the future of health starts with what’s on our plate?

Join Elysium and globally renowned nutrition scientist and cardiologist Dariush Mozaffarian, M.D., Dr.P.H. for an exclusive conversation about his new book, Food Is Medicine.

Drawing on more than 600 scientific publications, Dr. Mozaffarian challenges long-held ideas about fat, calories, processed foods, and what it really means to eat for health.

Plus: the first 500 attendees will receive a FREE copy of Food Is Medicine, ahead of its official release.

Register → https://events.zoom.us/ev/Auy7C5v0ja0r60pTGG8DfHo1giqkrr1ongJcVvsVghJwCfUulwmj~AsWiOdU2lwtgZTZ0w2V2h7sEjIfmSgX266aFgBsJ-3z53Zs6-lx7FceaGg

Cooler weather. A warm cup of coffee. And, perhaps, some ancient cellular biology.

New research suggests caffeine may activate AMPK, an ancient cellular energy sensor that helps cells respond to energy demands and stress. AMPK is involved in processes like cell growth, stress responses, and DNA repair—making it an intriguing pathway to study in the context of aging.

AMPK acts as a brake on TORC1, a well-studied lifespan regulator. When TORC1 is inhibited, cells shift away from growth and toward maintenance and survival. Interventions that inhibit TORC1, including rapamycin and dietary restriction, have been linked to lifespan extension across a wide range of model organisms, and those findings are an established cornerstone of aging biology.

One important caveat: this new research was conducted in yeast. The next question is whether caffeine activates the same pathway in humans.

Source: Alao, John-Patrick, et al. "Dissecting the cell cycle regulation, DNA damage sensitivity and lifespan effects of caffeine in fission yeast." Microbial Cell 12 (2025).

Sleep isn't downtime. It's when your brain runs maintenance.

New research from MIT found that pink noise bursts, precisely timed to the brain's own slow waves, strengthened the flow of cerebrospinal fluid (CSF) that helps clear waste from the brain.

This was a small study of 14 healthy adults, and it did not show that playing pink noise overnight has the same effect. But researchers want to explore whether enhancing this natural process could one day support healthier brain aging, so it's an area of study to watch.

Source: Levitt, Joshua, et al. "Closed-loop auditory stimulation in phase with slow waves during sleep enhances cerebrospinal fluid flow in humans." Science Translational Medicine 18.866 (2026).

As Healthy Aging Month comes to a close, it’s worth revisiting: What do we mean by “longevity”?

For us, it’s not just about adding years to life. It’s about extending the years we spend healthy, active, and able to do the things that make life worth living.

Longevity.Technology took a closer look at The Elysium Longevity Institute, our physician-led clinical program built around individualized care, clinical oversight, and rigorous standards.

“Our responsibility isn’t simply to make the latest advances in longevity science available,” said Elysium Co-Founder and CEO Eric Marcotulli. “It’s to evaluate them rigorously, deliver them responsibly, and continue contributing to the evidence that shapes the future of longevity medicine.”

Because longevity science advances are only part of the equation. The other is translating those advances into personalized, physician-guided care.

Read the full story: https://longevity.technology/news/elysium-opens-a-clinic-built-around-aging-well/

Creatine is having a bit of a rebrand.

Beyond building strength, it works in the body in more fundamental ways: replenishing cellular energy wherever your cells need it most—including the brain.

We built Creatine+ around that broader picture: pairing high-purity creatine with HMB and pomegranate polyphenols for strength, recovery, and cellular energy that goes beyond the gym.